Lortab is the mixture of hydrocodone and acetaminophen. Hydrocodone is an opioid while acetaminophen is a substance that is used in many over-the-counter cold medicines.

Lortab slows down the central nervous system, giving the user a greater resistance to pain, similar to other opioids. As a combination substance, Lortab can create additional side effects that most other opioids do not. The usual mood swings, insomnia and headaches occur. Lightheadedness, lack of motivation and body aches can also occur.

The first signs of Lortab addiction comes when one begins to stop using it for its intended purpose. This includes taking above the recommended dose, taking doses at inopportune times, using after it is no longer needed and using it simply to feel its effects.


Symptoms of withdrawal from Lortab include sleeping difficulty, appetite loss, restlessness, nausea and other feverish symptoms. Liver damage can also occur, as it contains acetaminophen.

Opiate Replacement Therapy (ORT) is an effective way to detox from opioids while diminishing the side effects of the withdrawal. This is done by using much weaker opioids to satisfy the brain’s needs as it gradually adjusts to returning to life without the opioid.

There are three different medications to choose from, and each may be better suited for someone depending on the person. The only drawback is that these substances also have the potential to be abused. Methadone and Suboxone are the first two substances. Methadone has a higher success rate, but also a higher rate of being abused due to being a weak opiate itself.

The other substance is Vivitrol, which is given once a month and is the safest option of the three, however in order for it to be safe, the patient must be fully detoxed of all alcohol and opiates.

Depending on one’s usage history, the length of Lortab detox can take anywhere between several days or months.